Tyro Pharma Quiz - 4

1. Cyclohexane can be used as a solvent in UV spectrophotometric analysis because
(A) It has a ring structure
(B) Energy requirement for σ − σ* is in the range of 120-200nm
(C) It is volatile
(D) It is immiscible with water
Option B
2. Quaternary structure in protein molecules refers to the
(A) Arrangement of multiple domains in a single polypeptide chain
(B) Specific arrangement of multiple subunits in multi-subunit proteins
(C) Formation of molten globules
(D) Protein folding in single subunit proteins
Option B
3. Interleukins are
(A) Polypeptide cytokines important in the inflammatory cascade
(B) Prostaglandins that account for gastrointestinal disorders
(C) Enkephalins which are specific for asthma
(D) Dipeptides which have antimicrobial properties
Option A
4. Phase I clinical studies of a drug under development is generally carried out on
(A) At least 10,000 people from different ethnic communities and a wide range of age groups
(B) A medium sized group of 500-1000 patients suffering from the disease for which the drug is being developed
(C) A small group of 20-100 healthy male and female volunteers
(D) Reliable in-vintro cell-lines derived from people suffering with the disease
Option C
5. A young patient complains that he gets severe shortness of breath whenever he takes aspirin for headache. Increased levels of a substance responsible for aspirin hypersensitivity is
(A) Prednisone
(B) Prostacycline
(C) Ibuprofen
(D) Leukotriene LTC4
Option B
Following are Matching exercises. Match group I with Group II and identify the correct combinations
(A) P-4, Q-3, R-1, S-2
(B) P-1, Q-2, R-4, S-3
(C) P-3, Q-4, R-2, S-1
(D) P-2, Q-1, R-3, S-4
Option C
(A) P-2, Q-1, R-4, S-3
(B) P-4, Q-3, R-1, S-2
(C) P-3, Q-4, R-2, S-1
(D) P-1, Q-2, R-3, S-4
Option C
(A) P-2, Q-3, R-4, S-1
(B) P-3, Q-4, R-1, S-2
(C) P-4, Q-1, R-2, S-3
(D) P-1, Q-2, R-3, S-4
Option A
(A) P-1, Q-2, R-3, S-4
(B) P-3, Q-4, R-1, S-2
(C) P-2, Q-3, R-4, S-1
(D) P-4, Q-1, R-2, S-3
Option B
(A) P-4, Q-1, R-2, S-3
(B) P-2, Q-3, R-4, S-1
(C) P-4, Q-3, R-2, S-1
(D) P-4, Q-2, R-3, S-1
Option B

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