Q.1 Digitalis toxicity is enhanced by co-administration of
(A) Potassium
(B) Quinidine
(C) Diuretics
(D) Antacids
Option B & C

Q.2 The rate limiting step in cholesterol biosynthesis is one of the followings :
(A) LDL-receptor concentration
(B) VLDL secretion
(C) Mevalonic acid formation
(D) Co-enzyme A formation
Option C

Q.3 Which one of the following drugs is withdrawn from the market due to torsade de pointes?
(A) Chlorpromazine
(B) Astemizole
(C) Haloperidol
(D) Domperidone
Option B

Q.4 Ganciclovir is mainly used for the treatment of infection caused by
(A) Cytomegalo virus
(B) Candida albicans
(C) Herpes zoster virus
(D) Hepatitis B virus
Option A & C
Q.5 Identify the one rational combination which has clinical benefit :
(A) Norfloxacin – Metronidazole
(B) Alprazolam – Paracetamol
(C) Cisapride – Omeprazole
(D) Amoxycillin - Clavulanic acid
Option D

Q.6 Stevens Johnson sjmdrome is the most common adverse effect associated with one of the following category of drugs :
(A) Sulphonamides
(B) Macrolides
(C) Penicillins
(D) Tetracyclines
Option A

Q.7 Amitryptyline is synthesized from the following starting material :
(A) Phthalic anhydride
(B) Terephthalic acid
(C) Phthalamic acid
(D) Phthalimide
Option B
Q.8 The common structural feature amongst the three categories of anticonvulsant drugs barbiturates, succinimides and hydantoins is
(A) ureide
(B) imidazolidinone
(C) dihydropyrimidine
(D) tetrahydropyrimidine
Option A

Q.9 Nicotinic action of acetylcholine is blocked by the drug
(A) Atropine
(B) Carvedilol
(C) Neostigmine
(D) d-Tubocurarine
Option D

Q.10 Chemical nomenclature of procaine is
(A) 2-Diethylaminoethyl 4-aminobenzoate
(B) N, N-Diethyl 4-aminobenzoate
(C) 4-Aminobenzamidoethyl amine
(D) 4-Amino-2-diethylaminoethyl benzoate
Option A & D

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